{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9663758","patent":{"patent_number":"US-9663758","title":"Global gene regulators (GGR) as vaccine candidates against paratuberculosis","assignee":null,"inventors":[],"filing_date":"2014-02-28T00:00:00.000Z","publication_date":"2017-05-30T00:00:00.000Z","cpc_codes":["C12Q","G01N","C12Q"],"num_claims":19,"abstract":"Described herein is a mycobacterium mutant, comprising at least one mutation in at least one gene sequence encoding global gene regulators (GGRs) selected from the group consisting of sigH, sigL, sigE, ECF-1, and mixtures thereof, wherein the GGR gene is at least partially inactivated. Described herein also is a vaccine based on the mutant and a method of differentiating between subjects that have been infected with mycobacterium and subjects that have not been infected with mycobacterium or have been vaccinated with a mycobacterium vaccine."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Global gene regulators (GGR) as vaccine candidates against paratuberculosis","description":"Described herein is a mycobacterium mutant, comprising at least one mutation in at least one gene sequence encoding global gene regulators (GGRs) selected from the group consisting of sigH, sigL, sigE","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9663758","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9663758","citation_suggestion":"Patentable. \"Global gene regulators (GGR) as vaccine candidates against paratuberculosis\" (US-9663758). https://patentable.app/patents/US-9663758","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9663758","json":"https://patentable.app/api/llm-context/US-9663758","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T05:20:38.110Z"}