{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9664689","patent":{"patent_number":"US-9664689","title":"Method for the selective detection and measurement of procalcitonin 1-116 and amino-terminal peptides of procalcitonin comprising amino acids 1 and 2 of procalcitonin 1-116","assignee":null,"inventors":[],"filing_date":"2013-01-14T00:00:00.000Z","publication_date":"2017-05-30T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N"],"num_claims":7,"abstract":"The present invention provides an immunodiagnostic method for determining procalcitonin and procalcitonin derivatives in a biological sample of a patient, in particular in the monitoring and control of treatment and the monitoring of the progression of a local or systemic bacterial infection, inflammation, sepsis or neurodegenerative disease. In particular, the method detects molecular forms of intact procalcitonin 1-116, or procalcitonin partial peptides derived therefrom that retain amino acids alanine and proline (Ala-Pro, AP) in positions 1 and 2 of the amino terminus of the complete procalcitonin 1-116. The method uses antibodies that selectively bind an epitope comprising amino acids 1 and 2 of procalcitonin 1-116 (SEQ ID NO: 1) and can distinguish between intact procalcitonin 1-116 and for example, procalcitonin 3-116."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method for the selective detection and measurement of procalcitonin 1-116 and amino-terminal peptides of procalcitonin comprising amino acids 1 and 2 of procalcitonin 1-116","description":"The present invention provides an immunodiagnostic method for determining procalcitonin and procalcitonin derivatives in a biological sample of a patient, in particular in the monitoring and control o","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9664689","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9664689","citation_suggestion":"Patentable. \"Method for the selective detection and measurement of procalcitonin 1-116 and amino-terminal peptides of procalcitonin comprising amino acids 1 and 2 of procalcitonin 1-116\" (US-9664689). https://patentable.app/patents/US-9664689","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9664689","json":"https://patentable.app/api/llm-context/US-9664689","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T08:00:41.048Z"}