{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9675623","patent":{"patent_number":"US-9675623","title":"Non-surgical method of treatment for cataract","assignee":null,"inventors":[],"filing_date":"2013-07-17T00:00:00.000Z","publication_date":"2017-06-13T00:00:00.000Z","cpc_codes":["B82Y","C12Q","G01N","G01N","G01N","G01N","G01N"],"num_claims":1,"abstract":"The invention provides inhibitors of α-crystallin aggregation and methods of using α-crystallin aggregation inhibitors to, e.g., treat or prevent cataracts in a subject having or at risk of developing cataracts. The invention further provides high throughput methods of screening compounds for modulation of protein thermal stability, the method comprising contacting a protein with each of a plurality of test compounds; and (b) measuring the melting transition (Tm) of the protein in the presence of each of the plurality of test compounds, wherein a compound that decreases or increases the apparent Tm by at least 2 standard deviations is identified as a pharmacological protein chaperone."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Non-surgical method of treatment for cataract","description":"The invention provides inhibitors of α-crystallin aggregation and methods of using α-crystallin aggregation inhibitors to, e.g., treat or prevent cataracts in a subject having or at risk of developing","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9675623","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9675623","citation_suggestion":"Patentable. \"Non-surgical method of treatment for cataract\" (US-9675623). https://patentable.app/patents/US-9675623","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9675623","json":"https://patentable.app/api/llm-context/US-9675623","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T07:20:03.336Z"}