{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9683238","patent":{"patent_number":"US-9683238","title":"Vascular endothelial growth factor-binding aptamers","assignee":null,"inventors":[],"filing_date":"2013-12-12T00:00:00.000Z","publication_date":"2017-06-20T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N","G01N"],"num_claims":11,"abstract":"Disclosed is providing a novel VEGF-binding aptamer whose affinity to VEGF is higher than those of known VEGF-binding aptamers. By an in silico maturation method starting from a known VEGF-binding aptamer, 4 kinds of aptamers whose affinities to VEGF are higher than that of the known VEGF-binding aptamer were prepared. By linking two molecules of an obtained aptamer to each other via a linker, an aptamer having an even higher affinity to VEGF was obtained. The polynucleotide of the present invention contains the base sequence of any one of SEQ ID NOs:1 to 4, and binds to vascular endothelial growth factor."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Vascular endothelial growth factor-binding aptamers","description":"Disclosed is providing a novel VEGF-binding aptamer whose affinity to VEGF is higher than those of known VEGF-binding aptamers. By an in silico maturation method starting from a known VEGF-binding apt","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9683238","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9683238","citation_suggestion":"Patentable. \"Vascular endothelial growth factor-binding aptamers\" (US-9683238). https://patentable.app/patents/US-9683238","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9683238","json":"https://patentable.app/api/llm-context/US-9683238","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T17:45:32.489Z"}