{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9689040","patent":{"patent_number":"US-9689040","title":"Selective inhibitors of tumor-initiating cells","assignee":null,"inventors":[],"filing_date":"2012-03-02T00:00:00.000Z","publication_date":"2017-06-27T00:00:00.000Z","cpc_codes":["C12Q","G01N","C12Q","G01N","G01N","G01N"],"num_claims":2,"abstract":"Described herein are novel malignancy associated gene signature biomarkers, and assays and methods thereof, to classify prognosis or malignant potential of a cancer and identify cancer-initiating cells. The malignancy associated gene signature biomarkers, assays and methods described herein provide, in part, new methodologies to screen for novel drugs for treating cancers and tumors, such as, for example, triple-negative breast tumors. Using the assays and methods described herein proteasome inhibitors, histone deacetylase inhibitors, and glycolysis inhibitors, were identified as being highly effective in altering gene expression signatures specifically in malignant or cancer-initiating cells."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Selective inhibitors of tumor-initiating cells","description":"Described herein are novel malignancy associated gene signature biomarkers, and assays and methods thereof, to classify prognosis or malignant potential of a cancer and identify cancer-initiating cell","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9689040","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9689040","citation_suggestion":"Patentable. \"Selective inhibitors of tumor-initiating cells\" (US-9689040). https://patentable.app/patents/US-9689040","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9689040","json":"https://patentable.app/api/llm-context/US-9689040","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T10:34:46.817Z"}