{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9695463","patent":{"patent_number":"US-9695463","title":"DNA 5-methyl cytosine demethylation activity of vertebrate DNA methyltransferases","assignee":null,"inventors":[],"filing_date":"2013-12-10T00:00:00.000Z","publication_date":"2017-07-04T00:00:00.000Z","cpc_codes":["C12Q","C12Q","C12Q","G01N","G01N"],"num_claims":20,"abstract":"Methods for identifying a test agent as a modulator of the active DNA demethylation activity of a DNA methyltransferase are disclosed. The method comprises: a) providing a methylated DNA; b) providing the DNA methyltransferase; c) allowing the methylated DNA to react with the DNA methyltransferase for a sufficient time to perform a demethylation reaction and generate a demethylated DNA product in the presence or absence of a test agent; d) analyzing the extent of demethylation; and d) comparing the extents of the demethylation in the presence and absence of the test agent, and thereby identify the test agent as a modulator of the DNA demethylation activity of the DNA methyltransferase."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"DNA 5-methyl cytosine demethylation activity of vertebrate DNA methyltransferases","description":"Methods for identifying a test agent as a modulator of the active DNA demethylation activity of a DNA methyltransferase are disclosed. The method comprises: a) providing a methylated DNA; b) providing","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9695463","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9695463","citation_suggestion":"Patentable. \"DNA 5-methyl cytosine demethylation activity of vertebrate DNA methyltransferases\" (US-9695463). https://patentable.app/patents/US-9695463","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9695463","json":"https://patentable.app/api/llm-context/US-9695463","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T13:37:08.797Z"}