{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9718858","patent":{"patent_number":"US-9718858","title":"Tunable control of protein degradation in synthetic and endogenous bacterial systems","assignee":null,"inventors":[],"filing_date":"2014-03-13T00:00:00.000Z","publication_date":"2017-08-01T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N"],"num_claims":9,"abstract":"The methods and compositions described herein relate, in part, to the generation of a synthetic degradation system in E. coli that provides tunable control of the protein level of targeted genes by using components of the Mesoplasma florum tmRNA system. Provided herein are degradation tag variants that permit independent control of both the initial level and inducible degradation rate of attached proteins."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Tunable control of protein degradation in synthetic and endogenous bacterial systems","description":"The methods and compositions described herein relate, in part, to the generation of a synthetic degradation system in E. coli that provides tunable control of the protein level of targeted genes by us","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9718858","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9718858","citation_suggestion":"Patentable. \"Tunable control of protein degradation in synthetic and endogenous bacterial systems\" (US-9718858). https://patentable.app/patents/US-9718858","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9718858","json":"https://patentable.app/api/llm-context/US-9718858","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T19:49:54.690Z"}