{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9726664","patent":{"patent_number":"US-9726664","title":"Animal model for diabetic complications","assignee":null,"inventors":[],"filing_date":"2011-11-14T00:00:00.000Z","publication_date":"2017-08-08T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N","G01N"],"num_claims":6,"abstract":"The invention relates to the surprising find that low density lipoprotein receptor-deficient mice (LDLr−/−) mice when fed with high energy diets produce controllable and consistent diabetic complications, especially renal damage, similar to the human pathophysiology and biological response. The invention thus comprises a method for discovering a preventive or therapeutic regimen for the prevention or treatment of diabetic micro- or macrovascular complications, comprising the steps of: a. feeding LDLr−/− mice, which have not been treated with streptozotocin, with a high energy diet; b. before, during and/or after this diet treating the mice with the preventive or therapeutic regimen; c. checking whether any change in the micro- or macrovascular system of the animal occurs. Specifically in such a method renal damage is assessed. Also use of said mice fed with a high energy diet for studying the diabetic micro- and macrovascular complications is part of the invention."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Animal model for diabetic complications","description":"The invention relates to the surprising find that low density lipoprotein receptor-deficient mice (LDLr−/−) mice when fed with high energy diets produce controllable and consistent diabetic complicati","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9726664","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9726664","citation_suggestion":"Patentable. \"Animal model for diabetic complications\" (US-9726664). https://patentable.app/patents/US-9726664","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9726664","json":"https://patentable.app/api/llm-context/US-9726664","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T13:37:14.192Z"}