{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9738898","patent":{"patent_number":"US-9738898","title":"Yeast cells expressing TAR DNA-binding protein 43 and uses therefor","assignee":null,"inventors":[],"filing_date":"2009-02-13T00:00:00.000Z","publication_date":"2017-08-22T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N"],"num_claims":26,"abstract":"Disclosed are yeast cells expressing TAR DNA-binding protein 43 (TDP-43) and methods of screening yeast cells to identify compounds that prevent or suppress TDP-43-induced toxicity, compounds that inhibit the formation or maintenance of cytoplasmic inclusions of TDP-43, genetic suppressors or enhancers of TDP-43-induced toxicity, and genetic suppressors or enhancers of the formation or maintenance of cytoplasmic inclusions of TDP-43. Compounds identified by such screens can be used to treat or prevent TDP-43 proteinopathies such as frontotemporal lobar degeneration or amyotrophic lateral sclerosis."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Yeast cells expressing TAR DNA-binding protein 43 and uses therefor","description":"Disclosed are yeast cells expressing TAR DNA-binding protein 43 (TDP-43) and methods of screening yeast cells to identify compounds that prevent or suppress TDP-43-induced toxicity, compounds that inh","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9738898","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9738898","citation_suggestion":"Patentable. \"Yeast cells expressing TAR DNA-binding protein 43 and uses therefor\" (US-9738898). https://patentable.app/patents/US-9738898","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9738898","json":"https://patentable.app/api/llm-context/US-9738898","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T15:32:40.215Z"}