{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9758809","patent":{"patent_number":"US-9758809","title":"RNA splicing alterations and U1 small nuclear ribonucleoproteins in neurodegenerative diseases","assignee":null,"inventors":[],"filing_date":"2014-03-06T00:00:00.000Z","publication_date":"2017-09-12T00:00:00.000Z","cpc_codes":["C12Q","C12Q","G01N","G01N","C12Q","G01N","G01N"],"num_claims":9,"abstract":"This disclosure relates to methods of diagnosing neurodegenerative disease by analyzing proteins or protein expression profiles in a subject, or RNA or RNA expression profiles in a subject. In certain embodiments, the disclosure contemplates the diagnosis of preclinical or symptomatic stages of Alzheimer's disease, mild cognitive impairment, or chronic traumatic encephalopathy by identification of components of U1 small nuclear ribonucleoproteins or fragments thereof which are capable of forming cytoplasmic tangle-like structures."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"RNA splicing alterations and U1 small nuclear ribonucleoproteins in neurodegenerative diseases","description":"This disclosure relates to methods of diagnosing neurodegenerative disease by analyzing proteins or protein expression profiles in a subject, or RNA or RNA expression profiles in a subject. In certain","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9758809","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9758809","citation_suggestion":"Patentable. \"RNA splicing alterations and U1 small nuclear ribonucleoproteins in neurodegenerative diseases\" (US-9758809). https://patentable.app/patents/US-9758809","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9758809","json":"https://patentable.app/api/llm-context/US-9758809","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T05:46:28.653Z"}