{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9765134","patent":{"patent_number":"US-9765134","title":"MZB1, a novel B cell factor, and uses thereof","assignee":null,"inventors":[],"filing_date":"2013-01-14T00:00:00.000Z","publication_date":"2017-09-19T00:00:00.000Z","cpc_codes":["G01N","G01N","G01N","G01N"],"num_claims":24,"abstract":"The marginal zone (MZ) and B1 subsets of B cells, which differ from conventional follicular (FO) B cells both developmentally and functionally, are involved in early responses to infectious pathogens and the production of self-reactive antibodies. A novel gene, mzb1, is expressed at high levels in MZ and B1 B cells but at low level, if at all, in FO B cells. MZB1 is involved in the regulation of proliferation, BCR-mediated signal transduction, and antibody production in B cells. Inhibitors, activators and enhancers of MZB1 expression or activity can be used as immune modulators for research and therapeutic purposes."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"MZB1, a novel B cell factor, and uses thereof","description":"The marginal zone (MZ) and B1 subsets of B cells, which differ from conventional follicular (FO) B cells both developmentally and functionally, are involved in early responses to infectious pathogens ","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9765134","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9765134","citation_suggestion":"Patentable. \"MZB1, a novel B cell factor, and uses thereof\" (US-9765134). https://patentable.app/patents/US-9765134","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9765134","json":"https://patentable.app/api/llm-context/US-9765134","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T15:32:11.361Z"}