{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9790329","patent":{"patent_number":"US-9790329","title":"Photoligation of an amphiphilic polymer with mixed coordination provides compact and reactive quantum dots","assignee":null,"inventors":[],"filing_date":"2015-03-30T00:00:00.000Z","publication_date":"2017-10-17T00:00:00.000Z","cpc_codes":["G01N","G01N"],"num_claims":17,"abstract":"The disclosure is directed to multi-coordinating polymers as ligands that combine two distinct metal-chelating groups, lipoic acid and imidazole, for the surface functionalization of QDs. These ligands combine the benefits of thiol and imidazole coordination to reduce issues of thiol oxidation and weak binding affinity of imidazole. The ligand design relies on the introduction of controllable numbers of lipoic acid and histamine anchors, along with hydrophilic moieties and reactive functionalities, onto a poly(isobutylene-alt-maleic anhydride) chain via a one-step nucleophilic addition reaction. We further demonstrate that this design is fully compatible with a novel and mild photoligation strategy to promote the in-situ ligand exchange and phase transfer of hydrophobic QDs to aqueous media under borohydride-free conditions. Ligation with these polymers provides highly fluorescent QDs that exhibit great long-term colloidal stability over a wide range of conditions."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Photoligation of an amphiphilic polymer with mixed coordination provides compact and reactive quantum dots","description":"The disclosure is directed to multi-coordinating polymers as ligands that combine two distinct metal-chelating groups, lipoic acid and imidazole, for the surface functionalization of QDs. These ligand","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9790329","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9790329","citation_suggestion":"Patentable. \"Photoligation of an amphiphilic polymer with mixed coordination provides compact and reactive quantum dots\" (US-9790329). https://patentable.app/patents/US-9790329","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9790329","json":"https://patentable.app/api/llm-context/US-9790329","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T12:20:59.409Z"}