{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9791453","patent":{"patent_number":"US-9791453","title":"Methods for determining binding capability of target ligands with G protein-coupled receptors using translocation through nanochannels","assignee":null,"inventors":[],"filing_date":"2012-12-26T00:00:00.000Z","publication_date":"2017-10-17T00:00:00.000Z","cpc_codes":["G01N","G01N"],"num_claims":27,"abstract":"A mechanism is provided for utilizing a nanodevice to distinguish molecules with different structure. The molecules translocate through or across a nanochannel filled with a electrolyte solution. An electrical signal through the nanochannel is measured for every translocation event. Inner surfaces of the nanochannel include a functional layer, which is a coating to functionalize the nanochannel, in which the functional layer is configured to interact with predetermined ones of the molecules during translocation events. It is determined that a combination of at least two different molecules is formed based on predetermined ones of the molecules interacting with the functional layer to change the electrical signal and/or change a translocation time for the translocation event."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Methods for determining binding capability of target ligands with G protein-coupled receptors using translocation through nanochannels","description":"A mechanism is provided for utilizing a nanodevice to distinguish molecules with different structure. The molecules translocate through or across a nanochannel filled with a electrolyte solution. An e","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9791453","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9791453","citation_suggestion":"Patentable. \"Methods for determining binding capability of target ligands with G protein-coupled receptors using translocation through nanochannels\" (US-9791453). https://patentable.app/patents/US-9791453","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9791453","json":"https://patentable.app/api/llm-context/US-9791453","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T07:27:26.453Z"}