{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9795665","patent":{"patent_number":"US-9795665","title":"Attenuated live vaccine for Crimean-Congo hemorrhagic fever virus and Erve virus","assignee":null,"inventors":[],"filing_date":"2013-08-13T00:00:00.000Z","publication_date":"2017-10-24T00:00:00.000Z","cpc_codes":["C12Q","G01N"],"num_claims":19,"abstract":"The genetically modified nairoviruses of this invention possesses a viral ovarian tumor protease with decreased ability to remove ubiquitin (Ub) and ISG15 tags that the human organism uses to label proteins for removal. Exemplary are Crimean-Congo hemorrhagic fever virus and Erve virus. Unlike complete knockout strains, the modified virus retains enough activity for replication in a human cell line. This creates an immunogenic and non-pathogenic virus that can be used as an effective live vaccine agent for prophylaxis and treatment."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Attenuated live vaccine for Crimean-Congo hemorrhagic fever virus and Erve virus","description":"The genetically modified nairoviruses of this invention possesses a viral ovarian tumor protease with decreased ability to remove ubiquitin (Ub) and ISG15 tags that the human organism uses to label pr","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9795665","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9795665","citation_suggestion":"Patentable. \"Attenuated live vaccine for Crimean-Congo hemorrhagic fever virus and Erve virus\" (US-9795665). https://patentable.app/patents/US-9795665","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9795665","json":"https://patentable.app/api/llm-context/US-9795665","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T14:38:16.283Z"}