{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9809595","patent":{"patent_number":"US-9809595","title":"Flagellar and needle complex (injectosome) loop as anti bacterial drug target","assignee":null,"inventors":[],"filing_date":"2014-02-27T00:00:00.000Z","publication_date":"2017-11-07T00:00:00.000Z","cpc_codes":["C12Q","C12Q","G01N","G01N"],"num_claims":4,"abstract":"The present invention relates to a method for screening a compound that inhibits secretion of toxins into host-cell cytoplasm by virulent bacteria using a needle type III secretion system. The compound of the invention is selected by screening for a compound which interacts with a loop region of the cytoplasmic domain of the membrane protein FlhB from Salmonella typhimurium or a paralog thereof. Compositions including the compound of the invention, use of the compound, and methods of treating disorders caused by virulent bacteria are also provided."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Flagellar and needle complex (injectosome) loop as anti bacterial drug target","description":"The present invention relates to a method for screening a compound that inhibits secretion of toxins into host-cell cytoplasm by virulent bacteria using a needle type III secretion system. The compoun","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9809595","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9809595","citation_suggestion":"Patentable. \"Flagellar and needle complex (injectosome) loop as anti bacterial drug target\" (US-9809595). https://patentable.app/patents/US-9809595","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9809595","json":"https://patentable.app/api/llm-context/US-9809595","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T05:35:17.092Z"}