{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9809839","patent":{"patent_number":"US-9809839","title":"Method for concentrating cells that are genetically altered by nucleases","assignee":null,"inventors":[],"filing_date":"2012-02-22T00:00:00.000Z","publication_date":"2017-11-07T00:00:00.000Z","cpc_codes":["C12Q","G01N"],"num_claims":17,"abstract":"The present invention relates to a reporter construct and method for identifying or enriching the cells, wherein a specific endogenous nucleotide sequence is cleaved by a specific nuclease or modified by such cleavage; a host cell comprising the reporter construct; and a system for monitoring a nuclease activity. The reporter system of the present invention is simple and non-invasive, and allows for an efficient enrichment of the gene-modified cells. Therefore, the present invention will promote the application of a nuclease in the field of gene therapy and genetic engineering as well as basic research."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"Method for concentrating cells that are genetically altered by nucleases","description":"The present invention relates to a reporter construct and method for identifying or enriching the cells, wherein a specific endogenous nucleotide sequence is cleaved by a specific nuclease or modified","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9809839","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9809839","citation_suggestion":"Patentable. \"Method for concentrating cells that are genetically altered by nucleases\" (US-9809839). https://patentable.app/patents/US-9809839","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9809839","json":"https://patentable.app/api/llm-context/US-9809839","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T18:31:12.256Z"}