{"schema_version":"1.0","canonical_url":"https://patentable.app/patents/US-9822414","patent":{"patent_number":"US-9822414","title":"In vitro method for predicting in vivo genotoxicity of chemical compounds","assignee":null,"inventors":[],"filing_date":"2012-05-19T00:00:00.000Z","publication_date":"2017-11-21T00:00:00.000Z","cpc_codes":["C12Q","G01N","G01N"],"num_claims":5,"abstract":"The invention is in the field of genomics and it provides an in vitro method for predicting whether a compound is genotoxic in vivo. In particular, the invention provides a method for predicting the in vivo genotoxicity of a compound comprising the steps of performing an Ames test on the compound and determining if the result is positive or negative, followed by a step wherein the gene expression of at least 3 genes is determined in a HepG2 cell, compared to a reference value and predicting that the compound is in vivo genotoxic if the expression level of more than 2 of the genes is above a reference value."},"analysis":{"summary":null,"layman_explanation":null,"technical_analysis":null,"business_analysis":null,"faqs":null,"topics":[],"tech_cluster":null},"seo":{"title":"In vitro method for predicting in vivo genotoxicity of chemical compounds","description":"The invention is in the field of genomics and it provides an in vitro method for predicting whether a compound is genotoxic in vivo. In particular, the invention provides a method for predicting the i","keywords":[]},"attribution":{"source":"Patentable","source_url":"https://patentable.app","canonical_url":"https://patentable.app/patents/US-9822414","license":"CC-BY-4.0-like","license_terms":"AI-generated analysis on this page (summary, layman_explanation, technical_analysis, business_analysis, faqs) may be reused with attribution and a visible link back to the canonical URL above. Patent abstracts, claims, and bibliographic data are USPTO public domain.","required_link":"https://patentable.app/patents/US-9822414","citation_suggestion":"Patentable. \"In vitro method for predicting in vivo genotoxicity of chemical compounds\" (US-9822414). https://patentable.app/patents/US-9822414","copyright_holder":"Nomic Interactive Technology LLC"},"links":{"html":"https://patentable.app/patents/US-9822414","json":"https://patentable.app/api/llm-context/US-9822414","site":"https://patentable.app","llms_txt":"https://patentable.app/llms.txt"},"generated_at":"2026-06-06T05:49:37.975Z"}