Legal claims defining the scope of protection. Each claim is shown in both the original legal language and a plain English translation.
1. A method for segmenting a two-dimensional angiographic recording of a vessel of a body by a computing apparatus, the method comprising: providing a three-dimensional reconstruction of the vessel of the body on the computing apparatus; providing the two-dimensional angiographic recording of the vessel of the body on the computing apparatus; registering the three-dimensional reconstruction of the vessel of the body with the two-dimensional angiographic recording of the vessel of the body; projecting spatial information of the three-dimensional reconstruction onto the two-dimensional angiographic recording, the projecting comprising detecting a variation between the spatial information of the three-dimensional reconstruction and corresponding spatial information of the two-dimensional angiographic recording and adjusting the two-dimensional angiographic recording based on the variation; and segmenting the two-dimensional angiographic recording using the spatial information projected onto the two-dimensional angiographic recording, wherein the adjusting comprises displacing, rotating, or displacing and rotating the two-dimensional angiographic recording, deforming the two-dimensional angiographic recording, or a combination thereof.
This invention relates to medical imaging, specifically segmenting two-dimensional angiographic recordings of blood vessels using three-dimensional vessel reconstructions. The problem addressed is the difficulty in accurately segmenting vessels in 2D angiographic images due to overlapping structures, noise, and limited contrast. The solution involves using a pre-existing 3D vessel reconstruction to enhance the segmentation process. The method begins by obtaining a 3D reconstruction of the vessel and a 2D angiographic recording of the same vessel. The 3D reconstruction is then registered (aligned) with the 2D angiographic image. Spatial information from the 3D model is projected onto the 2D image, where discrepancies between the 3D data and the 2D image are detected. The 2D image is adjusted based on these variations, which may involve displacement, rotation, deformation, or a combination of these transformations. Finally, the adjusted 2D image is segmented using the projected 3D spatial information, improving accuracy by leveraging the structural details from the 3D model. This approach enhances vessel segmentation in 2D angiographic images by integrating 3D anatomical data, reducing errors caused by image artifacts and overlapping structures.
2. The method of claim 1 , wherein the spatial information comprises at least one centerline of the vessel of the body that is projected onto the two-dimensional angiographic recording, and based on the at least one projected centerline, a centerline for the vessel of the body is determined on the two-dimensional angiographic recording and is used in the segmentation.
This invention relates to medical imaging, specifically the analysis of angiographic recordings to segment blood vessels in the body. The problem addressed is the accurate identification and segmentation of vessels in two-dimensional angiographic images, which is challenging due to overlapping structures, varying vessel diameters, and image noise. The method involves extracting spatial information from the angiographic recording, which includes at least one centerline of a vessel projected onto the two-dimensional image. This projected centerline is used to determine a corresponding centerline directly on the angiographic recording. The determined centerline is then utilized in the segmentation process to isolate the vessel structure from the surrounding tissue. This approach improves segmentation accuracy by leveraging the centerline as a reference point, reducing errors caused by image artifacts or complex vessel geometries. The method may also involve additional steps such as preprocessing the angiographic image to enhance vessel visibility, applying image processing techniques to refine the centerline, and using the centerline to guide boundary detection algorithms. The segmentation result can be used for diagnostic purposes, treatment planning, or further medical analysis. The invention enhances the reliability of vessel segmentation in angiographic imaging, supporting better clinical decision-making.
3. The method of claim 2 , wherein the at least one projected centerline is determined as a centerline for the vessel of the body on the recording and is used in the segmentation.
This invention relates to medical imaging and vessel segmentation, specifically improving the accuracy of vessel detection in recorded images. The problem addressed is the difficulty in precisely identifying vessel structures in medical recordings, which is critical for diagnostic and treatment planning. The invention enhances vessel segmentation by determining a projected centerline for the vessel in the recorded image and using this centerline as a reference during the segmentation process. The method involves analyzing the recorded image to identify the vessel structure and calculating a centerline that represents the central axis of the vessel. This centerline is then applied to guide the segmentation algorithm, ensuring that the vessel boundaries are accurately delineated. The use of a projected centerline improves segmentation accuracy by providing a structural reference that reduces errors caused by variations in vessel shape, contrast, or imaging artifacts. The invention may be used in various medical imaging modalities, including ultrasound, MRI, or CT scans, where precise vessel segmentation is essential for assessing conditions like atherosclerosis, aneurysms, or vascular malformations. By incorporating the centerline as a segmentation reference, the method ensures more reliable and consistent vessel boundary detection, aiding in clinical decision-making.
4. The method of claim 1 , wherein the spatial information comprises segmentation information of the three-dimensional reconstruction of the vessel of the body.
This invention relates to medical imaging, specifically methods for analyzing three-dimensional reconstructions of blood vessels in the body. The technology addresses the challenge of accurately segmenting and analyzing vascular structures from imaging data to improve diagnostic and treatment planning. The method involves generating a three-dimensional reconstruction of a vessel within the body using imaging data, such as computed tomography (CT) or magnetic resonance imaging (MRI). The key innovation is the inclusion of segmentation information within the spatial data of the reconstruction. This segmentation information identifies and distinguishes different regions or segments of the vessel, such as branches, bifurcations, or areas of stenosis, from the surrounding tissue. By incorporating segmentation data, the method enables precise analysis of vessel morphology, flow dynamics, and potential pathologies. The segmented reconstruction can be used to measure vessel dimensions, assess blood flow patterns, or identify abnormalities like blockages or aneurysms. This detailed spatial and structural information supports clinical decision-making, such as planning interventional procedures or evaluating treatment effectiveness. The method enhances existing imaging techniques by providing a more structured and interpretable representation of vascular anatomy, improving accuracy in diagnosis and treatment planning.
5. The method of claim 1 , wherein the three-dimensional reconstruction comprises a computed tomography or a magnetic resonance tomography.
This invention relates to medical imaging, specifically methods for generating three-dimensional (3D) reconstructions of anatomical structures using advanced imaging techniques. The problem addressed is the need for accurate and detailed 3D visualization of internal body structures to aid in diagnosis, treatment planning, and surgical guidance. Traditional imaging methods often provide limited spatial resolution or require invasive procedures, making non-invasive, high-resolution 3D reconstructions highly desirable. The method involves acquiring imaging data from a patient using either computed tomography (CT) or magnetic resonance tomography (MRT). These modalities are chosen for their ability to capture detailed cross-sectional images of the body. The acquired data is then processed to generate a 3D reconstruction, which provides a comprehensive view of the anatomical structures. This reconstruction can be used for various medical applications, including identifying abnormalities, planning surgical interventions, or monitoring disease progression. The use of CT or MRT ensures high-resolution imaging, allowing for precise visualization of tissues, organs, and other internal structures. The method may also include additional steps such as image segmentation, noise reduction, or enhancement techniques to improve the quality of the 3D model. The resulting 3D reconstruction can be displayed on a medical imaging system or integrated into surgical navigation tools to assist healthcare professionals in clinical decision-making.
6. The method of claim 1 , further comprising: minimizing the variation, the minimizing comprising adjusting the two-dimensional angiographic recordings, wherein the detecting is prior to or during use of the spatial information projected onto the two-dimensional angiographic recording.
This invention relates to medical imaging, specifically improving the accuracy of two-dimensional angiographic recordings by minimizing variations in spatial information. The problem addressed is the inherent distortion and variability in two-dimensional angiographic images, which can lead to inaccuracies in medical diagnosis and treatment planning. The invention provides a method to enhance the reliability of these recordings by adjusting the images to reduce variations, ensuring that the spatial information projected onto the angiographic recordings is consistent and accurate. The method involves detecting spatial information from the angiographic recordings, which can be performed before or during the projection of this information onto the two-dimensional images. By adjusting the recordings based on this detected spatial information, the method minimizes distortions and variations, resulting in more precise and reliable angiographic data. This adjustment process ensures that the spatial relationships within the recorded images are preserved, improving the overall quality and usability of the angiographic recordings for medical applications. The invention is particularly useful in scenarios where accurate spatial representation is critical, such as in vascular imaging and interventional procedures.
7. The method of claim 6 , wherein a diameter of the vessel of the body is retained.
This invention relates to medical devices and methods for treating blood vessels, particularly for maintaining vessel diameter during procedures. The problem addressed is the risk of vessel collapse or deformation during interventions such as angioplasty or stent placement, which can lead to complications like restenosis or inadequate blood flow. The method involves using a medical device to support the vessel wall while performing a procedure. The device includes an expandable structure, such as a balloon or stent, that is positioned within the vessel. The expandable structure is expanded to a predetermined diameter, which matches the natural diameter of the vessel, ensuring that the vessel retains its original size and shape. The device may also include sensors or imaging tools to monitor vessel dimensions in real-time, allowing for precise adjustment of the expandable structure to maintain the correct diameter. The method further includes steps for deploying the device within the vessel, expanding the structure to the desired diameter, and verifying that the vessel diameter is maintained throughout the procedure. The device may be designed to be removable after the procedure or to remain in place as a permanent implant, depending on the clinical needs. The invention aims to improve procedural outcomes by preventing vessel deformation and ensuring optimal blood flow.
8. The method of claim 7 , wherein a diameter of the vessel of the body is retained with a plastic deformation.
This invention relates to a method for retaining the diameter of a vessel in a body using plastic deformation. The method involves applying a force to the vessel wall to induce permanent deformation, ensuring the vessel maintains its desired diameter without relying on elastic recovery. This approach is particularly useful in medical applications where vessel patency must be preserved, such as in vascular interventions or stent deployment. The plastic deformation ensures long-term structural integrity, preventing collapse or narrowing of the vessel. The method may involve using a mechanical expansion tool or a deployable device that applies controlled pressure to the vessel wall, causing it to deform beyond its elastic limit. The deformation is permanent, ensuring the vessel retains its expanded state. This technique may be combined with other vessel treatment methods, such as stent placement or angioplasty, to enhance outcomes. The invention addresses the challenge of maintaining vessel patency in conditions like atherosclerosis or aneurysms, where vessel walls may weaken or narrow over time. By inducing plastic deformation, the method provides a durable solution for preserving vessel function.
9. The method of claim 6 , wherein the variation is minimized, such that a movement of the vessel of the body is compensated.
Technical Summary: This invention relates to a method for compensating for movement of a vessel within a body during a medical procedure, such as imaging or intervention. The problem addressed is the challenge of maintaining precise alignment or targeting when a vessel moves, which can occur due to physiological factors like respiration or cardiac cycles. The method involves minimizing variations in the position or orientation of a medical device relative to the vessel to ensure accurate and stable interaction. The method builds on a prior step of determining a reference position or trajectory for the medical device relative to the vessel. It then actively compensates for any detected movement of the vessel by adjusting the device's position or orientation in real-time. This compensation ensures that the device remains properly aligned with the vessel despite movement, improving the accuracy and reliability of the procedure. The compensation may involve feedback control systems, sensor-based tracking, or predictive algorithms to anticipate and counteract vessel motion. The goal is to maintain consistent contact or proximity between the device and the vessel, reducing errors and enhancing procedural outcomes. This approach is particularly useful in minimally invasive procedures where precision is critical.
10. The method of claim 9 , wherein the variation is minimized, such that a displacement of the vessel of the body caused by a breathing movement, a couch movement, a geometric shortening of the vessel of the body caused by a movement, or any combination thereof is compensated.
This invention relates to medical imaging and radiation therapy, specifically addressing the challenge of compensating for patient movement during procedures. The method involves minimizing variations in the position or geometry of a vessel within a patient's body to ensure accurate imaging or treatment delivery. The system detects and compensates for displacements caused by breathing, couch movement, or geometric changes in the vessel due to patient motion. By dynamically adjusting the imaging or treatment parameters in real-time, the method maintains precise alignment with the target vessel, improving the accuracy of diagnostic imaging or therapeutic interventions. The compensation mechanism may involve tracking the vessel's position using imaging sensors, adjusting the imaging or radiation beam path, or modifying the patient support system to counteract detected movements. This ensures consistent targeting despite physiological or mechanical disturbances, enhancing the reliability of medical procedures. The invention is particularly useful in scenarios where high precision is critical, such as in radiation therapy for cancer treatment or in vascular imaging.
11. The method of claim 1 , wherein the providing of the two-dimensional angiographic recording of the vessel, the registering, the projecting, and the segmenting are additionally carried out for one or more further two-dimensional angiographic recordings of the vessel of the body in place of the two-dimensional angiographic recording of the vessel of the body with the same three-dimensional reconstruction.
Medical imaging techniques, particularly in angiography, often struggle to accurately visualize and analyze blood vessels in three dimensions due to limitations in two-dimensional imaging. This can hinder diagnostic precision and treatment planning. A method addresses this by enhancing the accuracy of three-dimensional vessel reconstructions using multiple two-dimensional angiographic recordings. The method involves capturing multiple two-dimensional angiographic images of a vessel within a body. These images are registered to align them spatially, ensuring consistent positioning relative to a reference frame. The aligned images are then projected onto a three-dimensional reconstruction of the vessel, which serves as a foundational model. This projection allows for precise segmentation of the vessel structures within the two-dimensional images. The process is repeated for additional two-dimensional angiographic recordings of the same vessel, using the same three-dimensional reconstruction. This iterative approach improves the accuracy and detail of the vessel visualization by incorporating data from multiple angles or time points, reducing errors and enhancing diagnostic reliability. The method is particularly useful in medical applications requiring high-fidelity vessel imaging, such as cardiovascular diagnostics and interventional procedures.
12. The method of claim 11 , further comprising: generating a three-dimensional angiography of the vessel of the body from the two-dimensional angiographic recording and the one or more further two-dimensional angiographic recordings by the computing apparatus; and adjusting a three-dimensional structure of the vessel of the body in the three-dimensional angiography to a three-dimensional structure of the vessel of the body in the three-dimensional reconstruction.
This invention relates to medical imaging, specifically methods for generating and refining three-dimensional (3D) angiographic reconstructions of blood vessels in the body. The problem addressed is the limited accuracy of 3D vascular reconstructions derived from two-dimensional (2D) angiographic recordings, which can result in misalignment or distortion of the vessel structure. The method involves capturing multiple 2D angiographic recordings of a vessel from different angles. A computing apparatus processes these recordings to generate an initial 3D angiography of the vessel. To improve accuracy, the method further adjusts the 3D structure of the vessel in the angiography to match a pre-existing 3D reconstruction of the same vessel. This adjustment ensures that the final 3D angiography aligns with known anatomical or previously reconstructed data, enhancing precision. The technique leverages both new and existing 2D angiographic data to refine 3D vascular models, which can be critical for diagnostic or interventional procedures where accurate vessel visualization is essential. The adjustment step corrects discrepancies between the 3D angiography derived from 2D recordings and the reference 3D reconstruction, improving the reliability of the final output. This approach is particularly useful in scenarios where multiple imaging modalities or prior reconstructions are available.
13. The method of claim 1 , wherein the variation is minimized by adjusting the two-dimensional angiographic recording.
Technical Summary: This invention relates to medical imaging, specifically to improving the accuracy of two-dimensional angiographic recordings. Angiography is a diagnostic imaging technique used to visualize blood vessels, often to detect blockages or abnormalities. A common challenge in angiographic imaging is minimizing variations in the recorded images, which can arise from factors such as patient movement, equipment limitations, or inconsistent imaging parameters. These variations can lead to misdiagnosis or the need for repeated imaging procedures. The invention addresses this problem by adjusting the two-dimensional angiographic recording process to reduce such variations. The adjustment may involve modifying imaging parameters, such as exposure settings, frame rate, or the angle of the imaging device, to ensure consistency across multiple recordings. By minimizing variations, the method enhances the reliability of the angiographic data, improving diagnostic accuracy and reducing the need for repeat procedures. This adjustment can be applied in real-time during imaging or as a post-processing step to refine the recorded data. The technique is particularly useful in clinical settings where precise and consistent vascular imaging is critical for treatment planning.
14. An examination system for segmenting a two-dimensional angiographic recording of a vessel of a body, the examination system comprising: a medical imaging device configured to provide a three-dimensional reconstruction of the vessel of the body; an angiography device configured to provide the two-dimensional angiographic recording of the vessel of the body; and a computer that is coupleable to the medical imaging device, the computing apparatus being configured to: register the three-dimensional reconstruction of the vessel of the body with the two-dimensional angiographic recording of the vessel of the body; project spatial information of the three-dimensional reconstruction onto the two-dimensional angiographic recording; detect a variation between the spatial information of the three-dimensional reconstruction and corresponding spatial information of the two-dimensional angiographic recording; adjust the two-dimensional angiographic recording based on the variation; and segment the two-dimensional angiographic recording using the spatial information projected onto the two-dimensional angiographic recording, wherein adjusting the two-dimensional angiographic recording comprises displacing, rotating, or displacing and rotating the two-dimensional angiographic recording, deforming the two-dimensional angiographic recording, or a combination thereof.
This invention relates to a medical examination system for segmenting two-dimensional angiographic images of blood vessels. The system addresses the challenge of accurately analyzing vessel structures in angiographic recordings by integrating three-dimensional (3D) vessel reconstructions with two-dimensional (2D) angiographic data. The system includes a medical imaging device, such as a CT or MRI scanner, to generate a 3D reconstruction of the vessel, and an angiography device to capture the 2D angiographic recording. A computer processes these inputs by registering the 3D reconstruction with the 2D angiographic image, projecting spatial information from the 3D model onto the 2D image, and detecting discrepancies between the projected 3D data and the 2D recording. The system then adjusts the 2D image by displacing, rotating, deforming, or combining these adjustments to align the spatial information. Finally, the adjusted 2D image is segmented using the projected 3D spatial data, enabling precise vessel segmentation. This approach improves accuracy in vessel analysis by leveraging 3D anatomical context in 2D angiographic images.
15. The examination system of claim 14 , wherein the medical imaging device comprises a computed tomography (CT) device.
This invention relates to an examination system for medical imaging, specifically addressing the need for improved diagnostic accuracy and efficiency in medical imaging procedures. The system includes a medical imaging device, a patient support apparatus, and a control unit. The medical imaging device captures medical images of a patient, while the patient support apparatus positions and stabilizes the patient during imaging. The control unit processes the captured images to generate diagnostic data. The system is designed to enhance imaging precision, reduce patient discomfort, and streamline workflow in clinical settings. In one embodiment, the medical imaging device is a computed tomography (CT) scanner, which provides cross-sectional images of the body for detailed internal examination. The CT scanner operates by rotating an X-ray source around the patient while detectors capture transmitted radiation, generating high-resolution images used for diagnosing conditions such as tumors, fractures, or vascular abnormalities. The patient support apparatus ensures proper alignment and minimizes motion artifacts, while the control unit integrates image processing algorithms to optimize image quality and diagnostic output. This system improves upon prior art by combining advanced imaging technology with patient-centric design, enabling faster and more accurate diagnoses in medical practice.
16. The examination system of claim 14 , wherein the spatial information comprises at least one centerline of the vessel of the body that is projected onto the two-dimensional angiographic recording, and wherein the computer is configured to determine, based on the at least one projected centerline, a centerline for the vessel of the body on the two-dimensional angiographic recording and is configured to use the centerline for the vessel of the body in the segmentation.
This invention relates to medical imaging systems for examining blood vessels in a patient's body using angiographic recordings. The system addresses the challenge of accurately segmenting and analyzing vessels in two-dimensional angiographic images, where vessel boundaries can be difficult to distinguish due to overlapping structures or low contrast. The system includes a computer that processes angiographic recordings to extract spatial information about the vessels. This spatial information includes at least one centerline of the vessel, which is projected onto the two-dimensional image. The computer then determines a centerline for the vessel directly on the two-dimensional angiographic recording based on this projected centerline. This centerline is used to guide the segmentation process, improving the accuracy of vessel boundary detection. The segmentation may involve identifying the vessel walls or other structural features in the image. The system may also include additional components, such as an imaging device to capture the angiographic recordings and a display to visualize the segmented vessels. The computer may further analyze the segmented vessels to measure dimensions, detect abnormalities, or assist in medical diagnosis. The use of projected centerlines enhances the precision of vessel segmentation, particularly in cases where direct boundary detection is unreliable. This approach is useful in applications like vascular disease diagnosis, surgical planning, or interventional procedures.
17. The examination system of claim 16 , wherein the at least one projected centerline is determined as a centerline for the vessel of the body on the recording and is used in the segmentation.
This invention relates to medical imaging systems for examining blood vessels in a patient's body. The system addresses the challenge of accurately segmenting and analyzing vascular structures from recorded medical images, which is critical for diagnosing conditions like blockages or aneurysms. The system projects at least one centerline onto the recorded image of the vessel, which serves as a reference for segmentation. This centerline is calculated based on the vessel's geometry in the image and is used to guide the segmentation process, improving accuracy and efficiency. The segmentation may involve isolating the vessel from surrounding tissues or identifying specific regions of interest within the vessel. The system may also include additional features such as image enhancement, noise reduction, or automated measurement tools to further assist in vascular analysis. By using projected centerlines, the system ensures precise segmentation, which is essential for reliable diagnostic assessments. The technology is applicable in various medical imaging modalities, including angiography, ultrasound, or CT scans, and can be integrated into existing diagnostic workflows.
18. The examination system of claim 14 , wherein the spatial information comprises segmentation information of the three-dimensional reconstruction of the vessel of the body.
This invention relates to medical imaging systems for examining blood vessels in the human body. The system generates a three-dimensional reconstruction of a vessel, such as an artery or vein, using imaging data from techniques like computed tomography (CT) or magnetic resonance imaging (MRI). A key challenge in vascular imaging is accurately identifying and isolating the vessel structure from surrounding tissues to enable precise analysis. The system includes a segmentation module that processes the imaging data to extract spatial information, specifically segmentation data, which defines the boundaries and anatomical features of the vessel in three dimensions. This segmentation information allows for detailed visualization and measurement of the vessel, including its shape, size, and any abnormalities like blockages or aneurysms. The spatial data can be used for diagnostic purposes, treatment planning, or guiding minimally invasive procedures. The segmentation process may involve algorithms that differentiate vessel structures from other tissues based on intensity values, geometric properties, or machine learning techniques. The resulting segmented data is then integrated into the three-dimensional reconstruction, providing a clear and accurate representation of the vessel for medical professionals. This enhances diagnostic accuracy and supports interventions by offering a detailed, navigable model of the vascular system.
19. The examination system of claim 14 , wherein the computer is configured to minimize the variation, the minimization of the variation comprising adjustment of the two-dimensional angiographic recording.
This invention relates to an examination system for medical imaging, specifically for angiographic procedures where precise alignment and consistency of two-dimensional angiographic recordings are critical. The system addresses the problem of variations in angiographic images caused by patient movement, imaging device misalignment, or other factors, which can lead to inaccurate diagnoses or treatment planning. The system includes a computer that processes angiographic data to reduce these variations. The minimization of variation involves adjusting the two-dimensional angiographic recordings to ensure consistency across multiple images. This adjustment may include correcting for positional shifts, rotational misalignments, or other distortions that could affect the accuracy of the angiographic analysis. The system may also incorporate additional features such as real-time feedback or automated correction mechanisms to further enhance image stability. By minimizing variations in the angiographic recordings, the system improves the reliability of vascular imaging, aiding in more accurate diagnosis and treatment of cardiovascular conditions. The invention is particularly useful in clinical settings where precise image alignment is essential for procedures like stent placement, aneurysm detection, or vascular mapping.
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February 11, 2020
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