Systems, Methods and Apparatus to Process Medical Prescription Order Rejections

3. The method of claim 2, further including, when the third order for the medical prescription is approved, notifying the prescription fulfillment entity that the medical prescription is available to be fulfilled.

4. The method of claim 1, further comprising, when the second order is rejected, submitting the first order for manual review.

6. The method of claim 1, wherein the plurality of approved orders includes at least one of a third order generated by applying a plurality of rules, or a fourth order generated by manual review.

7. The method of claim 1, wherein the third-party entity includes at least one of an insurance company, a primary insurance company, a secondary insurance company, a government institution, a co-pay assistance program, a co-pay assistance organization, or a manufacturer.

10. The system of claim 9, wherein the first interface includes the second interface.

11. The system of claim 9, further including a rules-based handler configured to apply a plurality of rules to the first order to form a third order for the medical prescription, wherein the second interface is configured to submit the third order for the medical prescription to the third-party entity for payment, and wherein the machine learning model processes the input vector to form the second order when the third order is rejected by the third-party entity.

12. The system of claim 11, wherein the fulfillment system is configured to fill the medical prescription when the third order is approved.

13. The system of claim 9, wherein the third-party entity includes at least one of an insurance company, a primary insurance company, a secondary insurance company, a government institution, a co-pay assistance program, a co-pay assistance organization, or a manufacturer.

17. The non-transitory computer-readable storage medium of claim 16, wherein the instructions, when executed by one or more processors, cause the machine to, when the third order for the medical prescription is approved, notify the prescription fulfillment entity that the medical prescription is available to be fulfilled.

18. The non-transitory computer-readable storage medium of claim 15, wherein the instructions that, when executed by one or more processors, cause the machine to, when the second order is rejected, submit the first order for manual review.

19. The non-transitory computer-readable storage medium of claim 15, wherein the plurality of approved orders includes at least one of a third order generated by applying a plurality of rules, or a fourth order generated by manual review.