Systems and Methods for Optimizing Medical Care Through Data Monitoring and Feedback Treatment

1. A system for event-driven patient monitoring and treatment of a patient comprising: a plurality of physiological sensors configured to be coupled to the patient and configured to produce patient-specific data from the patient, the plurality of physiological sensors including at least a blood oximeter; a treatment device coupled to the patient and configured to administer a treatment to the patient under control of a computer; a processor; a memory coupled to the processor, the memory having computer-executable instructions stored thereon, which when executed by the processor, cause the processor to: receive patient-specific data associated with the patient, the patient-specific data comprising at least data from the blood oximeter coupled with the patient; determine a plurality of physiological variables based on the received patient-specific data, the plurality of physiological variables including at least oxygen saturation; define a state space with DO2 on a first axis and Qp/Qs on a second axis, the state space partitioned into a plurality of possible clinical patient states defined by a plurality of boundaries, the plurality of possible patient states comprising: (i) inadequate DO2 along with normal Qp/Qs, wherein normal Qp/Qs is greater than one but not greater than 1.5; (ii) adequate DO2 along with high Qp/Qs; and (iii) inadequate DO2 along with high Qp/Qs; determine from the patient-specific data, a current clinical patient state of the patient within the state space, the current clinical patient state being one of: (a) inadequate DO2 along with normal Qp/Qs; (b) adequate DO2 along with high Qp/Qs; and (c) inadequate DO2 along with high Qp/Qs; and send a signal to the treatment device coupled to the patient so that the signal causes the treatment device to administer a treatment to the patient, the treatment known to address the current clinical patient state.

2. The system of claim 1: wherein a boundary between adequate DO2 and inadequate DO2 is 25 ml O2/min/kg, and a boundary between normal Qp/Qs and high Qp/Qs is a ratio of 1.5, such that the patient state of adequate DO2 along with high Qp/Qs is defined by DO2 greater than 25 ml O2/min/kg along with Qp/Qs greater than a ratio of 1.5, and such that the patient state of inadequate DO2 along with high Qp/Qs is defined by DO2 less than 25 ml O2/min/kg along with Qp/Qs greater than a ratio of 1.5, and such that the patient state of inadequate DO2 along with normal Qp/Qs is defined by DO2 less than 25 ml O2/min/kg along with Qp/Qs less than a ratio of 1.5.

3. The system of claim 1, wherein (x) the treatment for inadequate DO2 along with normal Qp/Qs, and the treatment for inadequate DO2 along with high Qp/Qs, is administration of chronotropic medication; and (y) the treatment for adequate DO2 along with high Qp/Qs is administration of vasodilation medication.

4. A method for event driven patient monitoring and treatment of a patient comprising: coupling a plurality of physiological sensors to the patient, the plurality of physiological sensors configured to produce patient-specific data from the patient, the plurality of physiological sensors including at least a blood oximeter; coupling a treatment device to the patient, the treatment device configured to administer a treatment to the patient under control of a computer; receiving at a computer, patient-specific data associated with the patient, the patient-specific data comprising at least data from the blood oximeter coupled with the patient; determining, by the computer, a plurality of physiological variables based on the received patient-specific data; defining, by the computer, a state space with DO2 on a first axis and Qp/Qs on a second axis, the state space partitioned into the plurality of possible clinical patient states defined by a plurality of boundaries, including a boundary between adequate DO2 and inadequate DO2, and a boundary between normal Qp/Qs and high Qp/Q, the plurality of possible patient states comprising: (i) inadequate DO2 along with normal Qp/Qs, wherein normal Qp/Qs is greater than one but not greater than 1.5; (ii) adequate DO2 along with high Qp/Qs; and (iii) inadequate DO2 along with high Qp/Qs; determining, by the computer, from the physiological variables, a current clinical patient state within the state space, the current clinical patient state being one of: (a) inadequate DO2 along with normal Qp/Qs; (b) adequate DO2 along with high Qp/Qs; and (c) inadequate DO2 along with high Qp/Qs; and sending a signal from the computer to the treatment device coupled to the patient so that the signal causes the treatment device to administer a treatment to the patient, the treatment known to address the current clinical patient state.

5. The method of claim 4: wherein a boundary between adequate DO2 and inadequate DO2 is 25 ml O2/min/kg, and a boundary between normal Qp/Qs and high Qp/Qs is a ratio of 1.5, such that the patient state of adequate DO2 along with high Qp/Qs is defined by DO2 greater than 25 ml O2/min/kg along with Qp/Qs greater than a ratio of 1.5, and such that the patient state of inadequate DO2 along with high Qp/Qs is defined by DO2 less than 25 ml O2/min/kg along with Qp/Qs greater than a ratio of 1.5, and such that the patient state of inadequate DO2 along with normal Qp/Qs is defined by DO2 less than 25 ml O2/min/kg along with Qp/Qs less than a ratio of 1.5.

6. The method of claim 4, wherein (x) the treatment for inadequate DO2 along with normal Qp/Qs, and the treatment for inadequate DO2 along with high Qp/Qs, is administration of chronotropic medication; and (y) the treatment for adequate DO2 along with high Qp/Qs is administration of vasodilation medication.

7. A non-transitory computer-readable medium having computer-executable instructions stored thereon, the instructions executable by a computer, the instructions comprising: instructions to cause the computer to receive patient-specific data associated with the patient, the patient-specific data comprising at least data from one of the plurality of sensors coupled with the patient, the plurality of sensors including at least a blood oximeter; instructions to cause the computer to determine a plurality of physiological variables based on the received patient-specific data, the plurality of physiological variables including at least oxygen saturation; instructions to cause the computer to define a state space with DO2 on a first axis and Qp/Qs on a second axis, the state space partitioned into the plurality of possible clinical patient states defined by a plurality of boundaries, the plurality of possible patient states comprising: (i) inadequate DO2 along with normal Qp/Qs, wherein normal Qp/Qs is greater than one but not greater than 1.5; (ii) adequate DO2 along with high Qp/Qs; and (iii) inadequate DO2 along with high Qp/Qs; instructions to cause the computer to determine from the physiological variables, a current clinical patient state of the patient within the state space, the current clinical patient state being one of: (a) inadequate DO2 along with normal Qp/Qs; (b) adequate DO2 along with high Qp/Qs, and (c) inadequate DO2 along with high Qp/Qs; and instructions to cause the computer to control a treatment device by sending a signal to the treatment device coupled to the patient so that the signal causes the treatment device to administer a treatment to the patient, the treatment known to address the current clinical patient state.

8. The non-transitory computer-readable medium of claim 7: wherein a boundary between adequate DO2 and inadequate DO2 is 25 ml O2/min/kg, and a boundary between normal Qp/Qs and high Qp/Qs is a ratio of 1.5, such that the patient state of adequate DO2 along with high Qp/Qs is defined by DO2 greater than 25 ml O2/min/kg along with Qp/Qs greater than a ratio of 1.5, and such that the patient state of inadequate DO2 along with high Qp/Qs is defined by DO2 less than 25 ml O2/min/kg along with Qp/Qs greater than a ratio of 1.5, and such that the patient state of inadequate DO2 along with normal Qp/Qs is defined by DO2 less than 25 ml O2/min/kg along with Qp/Qs less than a ratio of 1.5.

9. The non-transitory computer-readable medium of claim 7, wherein (x) the treatment for inadequate DO2 along with normal Qp/Qs, and the treatment for inadequate DO2 along with high Qp/Qs is administration of chronotropic medication; and (y) the treatment for adequate DO2 along with high Qp/Qs is administration of vasodilation medication.

10. The system of claim 1, wherein sending a signal to the treatment device coupled to the patient so that the signal causes the treatment device to administer a treatment to the patient, the treatment known to address the current clinical patient state, comprises an ability to apply through dispensation of medication a treatment protocol.