8613937

Compositions and methods for biological remodeling with frozen particle compositions

PublishedDecember 24, 2013
Assigneenot available in USPTO data we have
Technical Abstract

Patent Claims
12 claims

Legal claims defining the scope of protection, as filed with the USPTO.

1

1. A frozen particle composition, comprising: one or more frozen particles including at least one biological remodeling agent of one or more of hyaluronic acid, keratin, polyaldehyde gluronate, glycosaminoglycan, poly (alpha-hydroxyacid), Type I collagen, Type II collagen, Type III collagen, Type VII collagen, Type X collagen, elastin fibers, or soluble elastin, wherein the frozen particles are coated with at least one of the biological remodeling agents.

2

2. The frozen particle composition of claim 1 , further comprising one or more of nitrogen, helium, neon, xenon, krypton, chlorine, bromine, or argon.

3

3. The frozen particle composition of claim 1 , wherein the one or more frozen particles have at least one major dimension of approximately one micrometer or less, approximately one nanometer or less, or any value therebetween.

4

4. The frozen particle composition of claim 3 , wherein the at least one major dimension includes at least one of the radius, diameter, length, width, height, or perimeter.

5

5. The frozen particle composition of claim 1 , wherein the at least one biological remodeling agent includes one or more extracellular matrix components.

6

6. The frozen particle composition of claim 1 , wherein the at least one biological remodeling agent is configured to promote growth of at least one biological tissue.

7

7. The frozen particle composition of claim 1 , wherein the at least one biological remodeling agent includes two or more components configured to combine upon deposition.

8

8. The frozen particle composition of claim 1 , further including at least one material that modulates the rate of diffusion or degradation of the at least one biological remodeling agent.

9

9. The frozen particle composition of claim 1 , wherein the at least one biological remodeling agent is included as part of a carrier that assists in synthesis or activation of the at least one biological remodeling agent.

10

10. The frozen particle composition of claim 1 , wherein the one or more frozen particles include a plurality of frozen particles that are approximately uniform in size, shape, weight, or density.

11

11. The frozen particle composition of claim 1 , further including at least one of a nanoparticle, or detection material.

12

12. A frozen particle composition, comprising: one or more frozen particles coated with at least one biological remodeling agent of one or more of hyaluronic acid, keratin, polyaldehyde gluronate, glycosaminoglycan, poly (alpha-hydroxyacid), Type I collagen, Type II collagen, Type III collagen, Type VII collagen, Type X collagen, elastin fibers, or soluble elastin, and the one or more frozen particles including at least one reinforcement agent of polyaramid, vinylester matrix, steel, ceramic, fiberglass, aromatic polyamide, nylon, silk, rayon, acetate, modacrylic, olefin, polyester, aromatic polyester, poly-lactic acid, vinyon, saran, spandex, vinalon, aromatic nylon, vinylidene chloride, modal, polybenzimidazole, lyocell, orlon, zylon, high-performance polyethylene, polypyridobenzimidazole, vectran, acrylonitrile rubber, glass, alluvium, diamond, novaculite, pumice, rouge, borazon, corundum, zirconia alumina, silicon, or silica; wherein the one or more frozen particles have at least one major dimension of approximately one micrometer or less.

Patent Metadata

Filing Date

Unknown

Publication Date

December 24, 2013

Inventors

Edward S. Boyden
Daniel B. Cook
Roderick A. Hyde
Eric C. Leuthardt
Nathan P. Myhrvold
Elizabeth A. Sweeney
Lowell L. Wood JR.

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Cite as: Patentable. “Compositions and methods for biological remodeling with frozen particle compositions” (8613937). https://patentable.app/patents/8613937

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