The present disclosure concerns inhibitors of Norovirus protease that are suitable for use against any genotype of Norovirus, including at least GII.4 Norovirus proteases. In particular embodiments, specific compositions are encompassed, including their use for prevention or treatment of Norovirus infection in an individual.
Legal claims defining the scope of protection, as filed with the USPTO.
1. A composition of matter, comprising compound 1076
2. A pharmaceutical composition, comprising the composition of claim 1 .
3. The pharmaceutical composition of claim 2 , wherein the composition is formulated in a cream, solution, pill, tablet, suppository, film, or enema.
4. A cleaning composition, comprising the composition of claim 1 .
5. The composition of claim 4 , wherein the composition is a solution or cream.
6. The composition of claim 4 , wherein the composition is in and/or on a substrate.
7. The composition of claim 6 , wherein the substrate is selected from the group consisting of a towel, a wipe, and a sponge.
Cooperative Patent Classification codes for this invention. Click any code to explore related patents in that topic.
October 5, 2017
May 31, 2022
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