An optical imaging system to image a target object includes a light source configured to emit one or more light rays to illuminate the target object and an image detector configured to capture a three-dimensional topography image of the target object when emitted light is emitted from the target object in response to being illuminated by the light rays emitted by the light source. A fluorescence image detector captures a fluorescence image of the target object when fluorescence is emitted from the target object in response illumination by light rays emitted by the light source. A controller instructs the image detector to capture the 3D topography image and the fluorescence image detector to detect the fluorescence image of the target object intraoperatively and to co-register and simultaneously display intraoperatively the co-registered topography and fluorescence information to the user via a display.
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2. The optical imaging system of claim 1, wherein the display is further configured to display at least the portion of the preoperative 3D topography of the target object via the corrected projection image with depth perception.
3. The optical imaging system of claim 1, further comprising a beam splitter, arranged between the target object and the image detection module, that is configured to split light based on polarization, wherein a portion of the split light is directed into the image detection module to enable polarization imaging of the target object, thereby enabling a depth-resolved topography of the preoperative image of the target object as captured by the image detection module.
5. The imaging system of claim 4, wherein the controller is further configured to instruct the display to enable the user to view the surrounding environment of the user via the display simultaneously with the display of the preoperative image data included in the corrected projection image that is co-registered to the intraoperative image data that is captured by the imaging system as the position of the target object is tracked by the tracker.
7. The imaging system of claim 6, wherein the controller is further configured to instruct the display to enable the user to view the surrounding environment of the user via the display simultaneously with the display of the intraoperative image data included in the corrected projection image that is co-registered with the intraoperative object space as the position of the target object is tracked by the tracker.
8. The imaging system of claim 7, wherein the controller is further configured to instruct the display to enable the user to view the surrounding environment of the user via the display simultaneously with the display of fluorescence image data included in the corrected projection image that is co-registered with the intraoperative object space.
9. The imaging system of claim 7, wherein the controller is further configured to instruct the display to enable the user to view the surrounding environment of the user via the display simultaneously with the display of color image data included in the corrected projection image that is co-registered with the intraoperative object space.
13. The method of claim 10, wherein the displaying comprises displaying the corrected projection image and enabling the user to view the surrounding environment of the user simultaneously via at least one wearable display.
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November 22, 2021
December 10, 2024
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