Magnetic control system base on measurement of target molecule adsorption

1. A portable magnetic-control measurement system, comprising: a reaction container configured to fill a target suspension having a plurality of magnetic nanoparticles (MNPs); a programable magnetron measurement unit comprises: an opaque housing; a loading platform configured to place the reaction container; a light-emitting device configured to generate a directional light through the reaction container; a magnetic field generator disposed on opposite two sides of the loading platform, to generate an alternating magnetic field forced on the reaction container in an operating time, wherein the magnetic field generator includes a linkage base and an electromagnet device, and the electromagnet device is detachably assembled to the linkage base; a sensing device configured to detect a light intensity variance of the directional light through the reaction container in the operating time; a processor communicatively coupled to the loading platform, the light-emitting device, the magnetic field generator and the sensing device, to calculate a value and an efficiency of absorption of the target suspension; a display communicatively coupled to the processor, to display the value and the efficiency of absorption of the target suspension; and a programmable logic controller and a step motor, a ball screw connected to the linkage base, wherein the programmable logic controller is communicatively coupled to the processor and the step motor, to receive a voltage signal from the processor and to control the step motor to drive the ball screw for changing a distance between the reaction container and the electromagnet device in a first direction.

2. The system of claim 1, wherein the operating time further comprises a starting time and an ending time, an initial data of light intensity at the starting time and a final data of light intensity at the ending time are formed by the sensing device respectively while the directional light through the reaction container, and the value and the efficiency of absorption of the target suspension are calculated respectively through the initial data of light intensity and the final data of light intensity by the processor.

3. The system of claim 2, wherein the efficiency of absorption of the target suspension is calculated according to the formula as below:, efficiency ⁢ ⁢ of ⁢ ⁢ absorption ⁢ ⁢ ( P ⁢ ⁢ 1 ) = Ci - Ce Ci - B parameter Ci is the initial data of light intensity, parameter Ce is the final data of light intensity, parameter B is the reference data of background.

4. The system of claim 1, wherein the target suspension is mainly a mixed solution, which is a biological molecular solution doped with a plurality of the magnetic nanoparticles (MNPs), and the biological molecular solution being selected from proteins, cells, strains, antibodies or drugs mixed with a solvent.

5. The device of claim 4, wherein the value of absorption of the target suspension is calculated according to the formula as below:, value ⁢ ⁢ of ⁢ ⁢ absorption ⁢ ⁢ ( P ⁢ ⁢ 2 ) = V × M × P ⁢ ⁢ 1 W parameter V is a volume of the biological molecular solution, parameter M is a concentration of the biological molecular solution before reacting, parameter W is a weight of the magnetic nanoparticles (MNPs) being doped, parameter P1 is the efficiency of absorption of the target suspension.

6. The device of claim 4, wherein the target suspension is synthesized by using co-precipitation in which the biological molecular solution and the magnetic nanoparticles (MNPs) are pre-mixed, and fill the target suspension into the reaction container.

7. The device of claim 1, wherein the opaque housing consists of an upper cover and a lower base, and the display is disposed on the upper cover for observing, and the upper cover is detachably assembled to the lower base to define a receiving space which all around is opaque, to receive the loading platform, the light-emitting device, the magnetic field generator and the sensing device.

8. The device of claim 7, wherein the programable magnetron measurement unit further comprises a control interface disposed on the upper cover for adjusting a plurality of operating parameters, which at least include a strength of alternating magnetic field and a frequency of alternating magnetic field.

9. The device of claim 8, wherein the operating parameters further include a light intensity of the light-emitting device and a distance between the reaction container and the magnetic field generator.

10. The device of claim 8, wherein the magnetic field generator further comprises a control circuit and the electromagnet device having an excitation coil, and there are two electromagnet devices movably disposed on opposite two sides of the loading platform along the first direction respectively, and the control circuit is communicatively coupled to the processor and the two electromagnet devices, to receive a voltage signal from the processor and to control the current flowing through the excitation coil for changing the strength of alternating magnetic field.

11. The device of claim 9, wherein the operating parameters further include a plurality of conditions of the operating time, which at least comprises a duration of the operation time, a number of operation cycles, and an interval time of an operation cycle.

12. The device of claim 11, wherein the operating parameters further include an operating condition of each operation in the operation cycle, which at least comprises the strength of alternating magnetic field, the frequency of alternating magnetic field, the light intensity of the light-emitting device, and the distance between the reaction container and the magnetic field generator.

13. The device of claim 10, wherein the loading platform further includes a fixing frame and a slide rail kit connected with the fixing frame, the slide rail kit comprises a supporting rail and a loading body, and the loading body having a groove portion on its surface of one side for inserting the reaction container, and the loading body having a slideway portion on its surface of another side, which is being slidably and separably connected to the supporting rail along a second direction.

14. The device of claim 13, wherein the first direction and the second direction are non-parallel.

15. The device of claim 13, wherein the upper cover further includes a gate door disposed near to the loading platform, and the gate door is openable and closable, and the loading body can be taken into inside of the opaque housing and connected to the supporting rail along the second direction while the gate door is open.

16. The device of claim 1, wherein the reaction container is a cassette-type box which is made of glass or plastic, and the reaction container has a light-penetration area and the light-penetration area is at least 60% of the reaction container.