The present invention relates generally to methods for assaying for agents that modify the association of Gsα with components of the plasma membrane or cytoskeleton of cells. The present invention also relates generally to methods of assaying for agents having antidepressant activity via analysis of the association of Gsα with components of the plasma membrane or cytoskeleton of cells using a fluorescent analog of Gsα and fluorescence resonance energy transfer (FRET).
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September 29, 2006
November 4, 2008
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