Patentable/Patents/US-8540664
US-8540664

Probablistic pharmacokinetic and pharmacodynamic modeling

PublishedSeptember 24, 2013
Assigneenot available in USPTO data we have
Inventorsnot available in USPTO data we have
Technical Abstract

The subject matter disclosed herein provides a response to a dose of a substance and/or controls the administration of the dose. In one aspect, there is provided a system. The system may include a processor and at least one memory configured to provide a response determinator. The response determinator may receive therapeutic and wellness data. Moreover, the response determinator may determine a response based on the received therapeutic and wellness data. The response may represent a reaction to a substance integrated with an ingestible event marker. The determined response may be provided to, for example, a therapy controller. Related systems, methods, and articles of manufacture are also described.

Patent Claims
11 claims

Legal claims defining the scope of protection, as filed with the USPTO.

2

2. The system of claim 1 , wherein the therapeutic and wellness data includes ingestible event marker data received from the ingestible event marker integrated with the substance, the ingestible event marker providing a signal when the substance is ingested.

3

3. The system of claim 1 , wherein the therapeutic and wellness data includes data representative of physiological aspects associated with the ingestion of the ingestible event marker and the substance.

4

4. The system of claim 1 , wherein the therapeutic and wellness data includes one or more of the following: an ingestion time; an identification of the substance; an expiration date of the substance; a dosage amount for the substance; one or more physiological parameters associated with the reaction to at least one dose of the substance; a dosage of an intravenous substance; a heart rate; a blood pressure measurement; an optical measurement; a body temperature; a weight; an amount of an inhalant; an inhalation time; an identity of an inhaled substance; a galvanic skin response; an insertion time; and a drinking time.

5

5. The system of claim 1 , wherein the response determinator determines the response as a function of the therapeutic and wellness data.

6

6. The system of claim 1 further comprising: a therapy controller configured to control, based on the response, at least one of an amount the substance and a time of the substance is ingested.

8

8. The system of claim 7 , wherein the therapy controller uses a closed-loop to control at least one of the dose of the substance and the time of the dose of the substance.

9

9. The system of claim 7 , wherein the therapy controller uses a closed-loop to vary an input to the response to generate an output of the response, the output corresponding to at least one of the dose of the substance and the time of the dose of the substance.

10

10. The system of claim 7 , wherein the ingestible event marker data are received from the ingestible event marker integrated with the substance, the ingestible event marker providing a signal when the substance is ingested.

11

11. The system of claim 7 , wherein the therapeutic and wellness data represents physiological aspects associated with the ingestion of the ingestible event marker and the substance.

12

12. The system of claim 7 , wherein the response is determined based on the reaction of at least one of an individual patient, a population, and a subset of the population.

13

13. The system of claim 7 , wherein the response is determined as a function of the therapeutic and wellness data.

Classification Codes (CPC)

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Patent Metadata

Filing Date

March 24, 2010

Publication Date

September 24, 2013

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Cite as: Patentable. “Probablistic pharmacokinetic and pharmacodynamic modeling” (US-8540664). https://patentable.app/patents/US-8540664

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